The Poser Paste hair makeup is washable, so it only stays on your head until you rinse it out. It comes in eight bright colors and, just like the semi-permanent dye, contains no parabens, phthalates, or sulfates.

The product contained paraphenylenediamine (PPD), a common ingredient in hair dyes, especially darker shades. PPD can also be found in henna tattoos, dark-colored makeup, photocopying and printing ink, black rubber, oil, greases, gasoline, and more. While not normally dangerous, if you are allergic to PPD, it can cause serious health issues.

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[A47B] TABLES; DESKS; OFFICE FURNITURE; CABINETS; DRAWERS; GENERAL DETAILS OF FURNITURE (jointing of furniture F16B 12/00)

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Here, a ternary heterostructure (Fig. 1), magnetic Fe3O4@GO@TiO2 (denoted as MGT), was developed (10), working as a plasmon-free SERS substrate with high molecular selectivity and stability, as well as a remarkable EF value of up to 8.08 × 106. This notable EF value was found to be mainly attributed to a high-efficiency interfacial CT process between GO and TiO2, which was verified by theoretical calculation and time-resolved diffuse reflectance (TDR) spectroscopic measurements. The present SERS substrate with high sensitivity and selectivity was developed to determine trace biological species, such as programmed cell death receptor ligand 1 (PD-L1, a model molecule), at the single-cell level. PD-L1 and its predominant target, programmed death 1 (PD-1), are two crucial immune checkpoint molecules tightly associated with immune resistance (11), which promote immune evasion and tumor recurrence and metastasis (12). PD-L1 is rarely expressed in regular epithelial tissues but is aberrantly expressed in many cancers, including breast (13), melanoma (14), and renal cell carcinoma (15). Immunotherapy using anti–PD-1 or anti–PD-L1 antibody (Ab) to block the interaction between PD-1 and PD-L1 has shown positive antitumor effects in clinical studies (16). Therefore, the quantitative characterization of PD-L1 expression on the cell surface has become an extremely important subject directly related to the development of diagnostic tools to guide PD-L1–based personalized treatment. A variety of analytical tools for PD-L1 monitoring have been reported during the past few years, such as immunohistochemical detection, mass spectrometry (MS), radiological imaging, flow cytometry, and positron emission tomography (17–21). To give a better understanding of the structural and functional roles that cells play in biological systems, it is necessary to develop a robust tool for the analysis and quantification of the components and metabolites in different individual cells (22). Developing a robust preliminary testing approach that provides reliable and quantitative diagnostic results in real time and in situ PD-L1 monitoring at the single-cell level remains a challenge. Triple-negative breast cancer cells (TNBCs) are types of cancer cells that always exhibit immune evasion and tumor recurrence and metastasis triggered by PD-L1 (12). In this experiment, we successfully used an MGT-based SERS probe to visualize and compare the expression and distribution of PD-L1 on three different kinds of TNBC surfaces at the single-cell level, which helped us to understand how PD-L1 behaves within different breast cancer genomic subtypes.

Bar Louie’s MacDonald Previews the New Year’s Eve Black & White Masquerade Party—Bar Louie’s MacDonald Previews…

Hazan says there’s no difference when it comes to covering up your grays or just simply switching up your regular color. "You can get them done like you normally would. It also depends on the amount of gray you have and the color you are going for," she says. "If you only have about 20 percent of your head covered in gray, you can use the highlights to mask them."

"Success is a Choice," which he co-wrote with Rick Pitino, is a business "how to" book that was a New York Times best-seller.

The Strasbourg-based court fined Lithuania €130,000 and Romania €100,000 over the treatment of the two men, who are still being held in Guantánamo Bay as suspected senior al-Qaeda operatives. It follows a similar ruling from the ECHR against Poland in 2014 over the same two men. 

The pigment’s vogue was short-lived, however. At the middle of the nineteenth century, Laughton Osborn advised, in his “Handbook of Young Artists and Amateurs in Oil Painting,” “There is nothing to be gained by smearing our canvas with a part perhaps of the wife of Potiphar.” When the painter of historical scenes Lawrence Alma Tadema told the Pre-Raphaelite painter Edward Burne-Jones that he was going to see pieces of mummy before they were turned into pigment, Burne-Jones, according to his wife, Georgina, snorted that the name of the pigment was just a childish fancy. On being assured that the mummy was real enough, Burne-Jones insisted on giving his own tubes of paint a burial in the garden. In fact, as Alison Cariens, the conservation coördinator for the Straus Center, explained, scientists have found no DNA in the Forbes’s samples of Mummy to suggest that it contained human bones, but the biological material may have degraded beyond reliable analysis over the millennia. In any case, she added, humans were often accompanied by mummified animals on their journey to the afterworld, so that a tube of Mummy Brown might well contain the remains of crocodiles or cats.