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Mrs. Ivey had moved back home to Cedartown after living in Florida for many years. She always loved to go shopping or simply spend time working in the garden, but her greatest joy was her family who always had a special place in her heart.

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“Tariffs have caused some customers to rethink their supply chain and manufacturing locations, and that does affect PolyOne,” he added. “Thankfully…we’re well-positioned to serve the needs of our customers, regardless of where they operate.”

Funeral services were held Wednesday, April 25, 2018 at 2 p.m. in the chapel of the Alvis Miller and Son Funeral Home with Rev. Tommy Harris officiating and eulogies given by his family. Interment followed in the Taylorsville Cemetery.

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We know that the I-quartet channels are spontaneously inserted into lipid bilayers (12, 14). Among the various methods that can be used to analyze the interactions between the I-quartets and an SLB, the QCM-D technique (25–27) allows detection of mass changes at the sensor surface based on the reciprocal piezoelectric effect (28). As previously observed, the formation of the SLB from small unilamellar vesicles (SUVs) follows a two-step mechanism: (i) fast adsorption of the SUVs to the QCM-D silica crystal with increased mass (that is, decreased ΔF, frequency) and increased layer flexibility (that is, increased ΔD, dissipation coefficient), because floppy SUVs were deposited on the QCM-D sensor, and (ii) rupture and fusion of SUVs into SLBs (ΔF minimum and ΔD maximum) (Fig. 2) (25). A final buffer wash was included to allow complete annealing of the SLB (29, 30). In particular, for the case of a molar composition of 4:1 = phosphatidylcholine (PC)/phosphatidylserine (PS) and HC8, a ΔF of −25.3 Hz was observed (Fig. 2B), corresponding to a total mass of 352 ng (that is, mL = 217 ng, mHC8 = 54 ng, mW,hydration layer = 79 ng, and mW,channel = 1.8 ng), which demonstrated the formation of a stable SLB on the QCM-D surface (the calculations were based on the total insertion of HC8 into the vesicles). The formation of an SLB, with or without HC8, was also tested for 4:1 = PC/PS + 20% w/w cholesterol (Chl) and PC (fig. S2). Whereas the addition of Chl did not affect the formation of an SLB, the PC-alone SUVs failed to form an SLB. In addition, on the basis of the ΔF values, the addition of HC8 caused a decrease of the bilayer thickness from 4.61 nm (that is, 4:1 = PC/PS alone) to 4.48 nm (4:1 = PC/PS with HC8) (see paragraph 2.4.1 in note S1 of the Supplementary Materials). This measure demonstrated the formation of a more compact structure and the partial contraction of the SLB when HC8 was incorporated. A more compact structure compared with the pure SLB is most likely the result of global SLB stabilization via supplementary phospholipid headgroup/imidazole electrostatic interactions and hydrophobic contact between the lipid and alkyl tails toward the bilayer aggregation. Together, these results demonstrate the incorporation of I-quartet channels into a supported 4:1 = PC/PS SLB that was selected for SFG experiments presented below. About 0.7% of the total mass of the SLBs comprises water wires in the system (see note S1 and figs. S2 to S5 for detailed calculations).

Inventor(s): Alexei Sadovnikov (Sunnyvale, CA), Andrew D. Strachan (Santa Clara, CA), Dening Wang (McKinney, TX), Gang Xue (San Jose, CA) Assignee(s): TEXAS INSTRUMENTS INCORPORATED (Dallas, TX) Law Firm: No Counsel Application No., Date, Speed: 15679592 on 08/17/2017 (481 days app to issue)

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"Previous work we have done described the oldest fossils of Metrosideros (scientific name for the species) from…35-40 million years ago in Tasmania, showing that the genus once did occur in Australia but has since become extinct," Tarran added.

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Yale researchers Jared Rovny, left, Robert Blum, center, and Sean Barrett, right, made the discovery. Credit: Yale University "We decided to try searching for the DTC signature ourselves," said Yale physics professor Sean Barrett, principal investigator for the two new studies. "My student Jared Rovny had grown monoammonium phosphate (MAP) crystals for a completely different experiment, so we happened to have one in our lab."


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