More information: Tim Gruene et al. Rapid structure determination of microcrystalline molecular compounds using electron diffraction, Angewandte Chemie International Edition (2018). DOI: 10.1002/anie.201811318

1. Check the Label.  Any product that contains lead acetate must contain a warning statement. Therefore, checking for that warning can be very beneficial. Review the product’s ingredient declaration found on the label to see if your hair dye contains lead.

For structural biologists, the first step in determining a protein’s precise molecular structure is often the hardest: coaxing the protein to grow into the orderly, three-dimensional crystals that are the starting material …

We have firmer geographic constraints on these populations after about 12,600 years ago. Ancient Beringians, associated with the Denali complex/Paleoarctic tradition, were in Alaska and adjacent areas between 12,500 and 6000 years ago (19). Although the northern lineage (including Na-Dene, Algonquian, Salish, Tsimshian, and Haida) appears constrained to northern North America (33), the southern lineage directly links with Clovis (Anzick) (16–18). However, we have no direct genetic evidence arising from populations associated with pre-Clovis sites linking them with later Native Americans. Thus, we should be careful to distinguish potential failed migrations versus the direct ancestors of Clovis and later Paleoindians. We also note that pre-Clovis sites continue to vary in site integrity, that is, clear associations of secure dates and unambiguous cultural materials. There appear to be relatively few technological or adaptive connections among the proposed pre-Clovis sites, or with (later) unequivocal Paleoindian complexes, represented by hundreds of sites and thousands of artifacts across the Americas (34, 35). However, analyses by (36) have shown that currently dated Clovis sites represent a sample that came from a population of sites that date to a time span covering 1070 to 835 years. This suggests that it is possible that some pre-Clovis sites after ~15,000 years ago may represent Clovis ancestors or are Clovis sites that lack diagnostic artifact types.

Abstract: Electrical charging device chassis and cases are provided herein. An example charging case includes a device receiving tray, a sliding tray having a charging interface, and a stabilizer. The sliding tray translates relative to the device receiving tray to extend and retract the charging interface using a track and gear assembly.

With seven high performance microphones to pick up commands, the echo dot can control Alexa-compatible smart home devices, stream music and make audio calls between Echo devices and the Alexa app.

Besides, cMGT was synthesized by a similar process. Typically, MG was dispersed in a mixture of 25 ml of ethanol and 7 ml of acetonitrile under vigorous stirring. After the addition of 0.2 ml of ammonia aqueous solution, 0.3 ml of TBOT in 3 ml of ethanol and 1 ml of acetonitrile was injected into the mixture. After stirring for 3 hours, the particles were centrifuged and washed with water and dried in an oven at 80°C for 6 hours.

We measured several characteristics of water molecules and imidazoles in the MD simulations (table S4). The number of water molecules within the membrane region is similar for the R-HC8 and S-HC8 constructs, 68 and 65, respectively, and is significantly higher than for the HC8 system featuring 39 water molecules. This results in the formation of water wires of roughly 3.5 nm in length, much longer than the length of ~1.0 nm of the water wires observed in the selectivity filter of AQP (22). We previously characterized the structure of I-quartet channels in the membrane region and concluded that the most representative channels in our simulation setup are the two central ones, which are less perturbed by boundary effects than the more exposed lateral ones (14). Hence, most of the simulation analysis focuses on these two central channels depicted in Fig. 4A. The visually apparent water ordering and orientation is in part due to anchoring sites provided by the imidazole structure across the membrane. Another contribution to water structuring originates in the electrostatic field generated by the ensemble of charges in the I-quartet system as depicted in Fig. 4B. A positive to negative potential field gradient builds up from bottom to top, driven by an additive effect of the orientation and ordering of imidazole dipoles, which seems to be highly correlated with the membrane contractions observed from QCM-D experiments. Qualitatively, this effect seems proportional to the preserved ordering of the imidazoles and decreases from R-HC8 to S-HC8 and HC8.

The ECHR was unable to interview either of the men and so instead had to rely on public information, including a 2014 US Senate report on CIA torture. 

Abstract: A method includes acquiring magnetic data from a magnetometer, processing the magnetic data to perform robust calibration, and generating optimum calibration parameters using a calibration status indicator. To that end, the method includes generating a calibration status indicator as a function of time elapsed since a last calibration and variation in total magnetic field in previously stored magnetic data, detecting anomalies, and extracting a sparse magnetic data set using comparison between the previously stored magnetic data and the magnetic data. Calibration parameters are generated for the magnetometer using a calibration method as a function of the magnetic data set. The calibration parameters are stored based on performing a validation and stability check on the calibration parameters, and weighted with the previously stored calibration parameters to produce weighted calibration parameters. Calibration settings are generated as a function of the weighted calibration parameters, if the weighted calibration parameters were produced.

AA Car Essentials Emergency Winter Car Kit – now: £24.60, was: £34.99 – available until November 30

Inventor(s): Ahmad Bahai (Lafayette, CA), Ali Kiaei (San Jose, CA), Baher Haroun (Allen, TX), Reza Hoshyar (San Jose, CA), Wenting Zhou (Milpitas, CA) Assignee(s): TEXAS INSTRUMENTS INCORPORATED (Dallas, TX) Law Firm: No Counsel Application No., Date, Speed: 15281617 on 09/30/2016 (802 days app to issue)